Evaluating the effect of green tea intake on cardiovascular diseases: A Mendelian randomization study in European and East Asian populations.

ABSTRACT: Previous research shows that more than 70% of cardiovascular diseases (CVDs) are attributed to modifiable risk factors. Here, we investigated relationship between consumption of green tea in European and East Asian populations and risk of CVDs using Mendelian randomization (MR). Instrumental variables for green tea intake were obtained from genome-wide association studies (GWASs) of 64,949 Europeans and 152,653 East Asians. GWASs for CVDs were derived from UK BioBank and BioBank Japan projects. The main method selected for MR analysis was either the inverse variance weighted (IVW) or Wald ratio, depending on the quantity of single nucleotide polymorphisms. Furthermore, we performed sensitivity analyses to confirm the reliability of the findings. Based on the results of IVW, there is no cau

SUBMITTER: Liang Q 

PROVIDER: S-EPMC11398782 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature