Provincial and connector qualities of somatosensory brain network hubs in bipolar disorder.

ABSTRACT: Brain network hubs are highly connected brain regions serving as important relay stations for information integration. Recent studies have linked mental disorders to impaired hub function. Provincial hubs mainly integrate information within their own brain network, while connector hubs share information between different brain networks. This study used a novel time-varying analysis to investigate whether hubs aberrantly follow the trajectory of other brain networks than their own. The aim was to characterize brain hub functioning in clinically remitted bipolar patients. We analyzed resting-state functional magnetic resonance imaging data from 96 euthymic individuals with bipolar disorder and 61 healthy control individuals. We characterized different hub qualities within the somatomotor net

SUBMITTER: Klahn AL 

PROVIDER: S-EPMC11398877 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature