The role of resection in hepatocellular carcinoma BCLC stage B: A multi-institutional patient-level meta-analysis and systematic review.

ABSTRACT:

Purpose

The Barcelona Clinic Liver Cancer (BCLC) staging schema is widely used for hepatocellular carcinoma (HCC) treatment. In the updated recommendations, HCC BCLC stage B can become candidates for transplantation. In contrast, hepatectomy is currently not recommended.

Methods

This systematic review includes a multi-institutional meta-analysis of patient-level data. Survival, postoperative mortality, morbidity and patient selection criteria for liver resection and transplantation in BCLC stage B are explored. All clinical studies reporting HCC patients with BCLC stage B undergoing liver resection or transplantation were included.

Results

A total of 31 studies with 3163 patients were included. Patient level data was available for 580 patients from 9 studies (423 afte

SUBMITTER: Lopez-Lopez V 

PROVIDER: S-EPMC11399194 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature