The impact of hypertension on clinical outcomes in moyamoya disease: a multicenter, propensity score-matched analysis.

ABSTRACT:

Background

Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by progressive steno-occlusive changes in the internal carotid arteries, leading to an abnormal vascular network. Hypertension is prevalent among MMD patients, raising concerns about its impact on disease outcomes. This study aims to compare the clinical characteristics and outcomes of MMD patients with and without hypertension.

Methods

We conducted a multicenter, retrospective study involving 598 MMD patients who underwent surgical revascularization across 13 academic institutions in North America. Patients were categorized into hypertensive (n=292) and non-hypertensive (n=306) cohorts. Propensity score matching (PSM) was performed to adjust for baseline differences.

Results

The mean a

SUBMITTER: Musmar B 

PROVIDER: S-EPMC11399283 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature