SARS-CoV-2 seroprevalence in people living with HIV in South Sudan.

ABSTRACT:

Objectives

The burden of SARS-CoV-2 infection in people living with HIV (PLHIV) in South Sudan is unknown.

Methods

We conducted a cross-sectional seroprevalence survey of SARS-CoV-2 immunoglobulin (Ig) G antibodies and other diseases of public health importance (strongyloidiasis, toxoplasmosis) in PLHIV in South Sudan during April 1, 2020-April 30, 2022. We used a multiplex SARS-CoV-2 immunoassay to detect IgG antibodies targeting the SARS-CoV-2 spike, receptor binding domain, and nucelocapsid (N) proteins, and antigens for other pathogens (Strongyloides stercoralis and Toxoplasma gondii).

Results

Among 3518 samples tested, seroprevalence of IgG antibodies to SARS-CoV-2 spike protein and receptor binding domain 591 and nucleocapsid ranged from 1.4% (95% confide

SUBMITTER: Chun HM 

PROVIDER: S-EPMC11399597 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature