Stereotactic body radiation therapy in non-liver colorectal metastases: a scoping review.

ABSTRACT:

Background

In oligometastatic colorectal cancer (CRC), stereotactic body radiation therapy (SBRT) represents a valid non-invasive local ablative treatment with high rates of local control (LC) and a low toxicity profile. This literature review was performed to evaluate the clinical benefit and toxicity of SBRT on non-liver metastases in CRC oligometastatic patients.

Methods

After searching PubMed, Medscape and Embase databases, 18 retrospective studies focused on body oligometastases excluding bone metastases were included in the analysis.

Results

A total of 1,450 patients with 3,227 lung metastases and 53 patients with 66 nodes lesions were analyzed. BED10 ranged from 76 to 180 Gy. In the lung group, the LC rate was 62-91%, 54-81% and 56-77% after 1, 3 and 5 years, r

SUBMITTER: Teriaca MA 

PROVIDER: S-EPMC11399829 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature