Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) combined with conventional MRI for the detection of skull-base invasion in nasopharyngeal carcinoma: comparison with ¹⁸F-sodium fluoride (¹⁸F-NaF) positron emission tomography/computed tomography (PET/CT).

ABSTRACT:

Background

The extent of skull base invasion (SBI) in nasopharyngeal carcinoma (NPC) directly impacts tumor staging, treatment strategies, and prognosis assessment for NPC patients, emphasizing the critical need for prompt diagnosis and precise assessment of invasion. Thus, we aimed to integrate the advantages of intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) and conventional magnetic resonance imaging (cMRI), and assess their combined diagnostic efficacy versus that of ¹⁸F-sodium fluoride (¹⁸F-NaF) positron emission tomography/computed tomography (PET/CT) for detecting SBI in NPC patients.

Methods

The study prospectively and randomly recruited 62 patients newly diagnosed with NPC by pathological biopsy at the Cancer Center of Affili

SUBMITTER: Li Y 

PROVIDER: S-EPMC11400646 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature