Impact of nitroglycerin on machine-learning fractional flow reserve in coronary computed tomography (CT)-angiography.

ABSTRACT:

Background

Nitroglycerin administration prior to examination improves stenosis assessment of coronary computed tomography (CT) angiography (CCTA). However, whether nitroglycerin influences CT-derived fractional flow reserve (FFR, CT-FFR) evaluation remains unclear. This study aimed to investigate the effect of nitroglycerin on diagnostic performance of CT-FFR.

Methods

In this single-center retrospective study, 107 consecutive patients suspected of coronary artery disease (CAD) with nitroglycerin administration prior to CCTA in 2019 were matched to 107 patients without nitroglycerin in 2016 from Fuwai Hospital. All patients underwent CCTA and invasive FFR in a month. Vessel-based and patient-based accuracy and diagnostic performance of CT-FFR were compared between the two gro

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC11400661 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature