Prognostic significance of diffuse increased fluorine-18-fluorodeoxyglucose (¹⁸F-FDG) uptake within the reticuloendothelial system in lymphoma patients.

ABSTRACT:

Background

As constituents of the reticuloendothelial system, the spleen and bone marrow (BM) have been recognized as integral components of the systemic inflammatory response in cancer contexts, thereby serving as predictive indicators for assessing cancer prognosis. Fluorine-18-fluorodeoxyglucose (¹⁸F-FDG) positron emission tomography (PET)/computed tomography (CT) has attained widespread utilization for staging, assessing treatment response, and prognostication in lymphoma patients. Several investigations have proposed that focal increased ¹⁸F-FDG uptake in the BM or spleen may correlate with malignant involvement in lymphoma. However, scant data exist regarding the implications of diffuse BM and splenic uptake. This study aimed to explore the relationships

SUBMITTER: Zhao Z 

PROVIDER: S-EPMC11400674 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature