Sex differences in treatment of familial hypercholesterolaemia: a meta-analysis.

ABSTRACT:

Background and aims

Familial hypercholesterolaemia (FH) is a highly prevalent monogenic disorder characterized by elevated LDL cholesterol (LDL-C) levels and premature atherosclerotic cardiovascular disease. Sex disparities in diagnosis, lipid-lowering therapy, and achieved lipid levels have emerged worldwide, resulting in barriers to care in FH. A systematic review was performed to investigate sex-related disparities in treatment, response, and lipid target achievement in FH (PROSPERO, CRD42022353297).

Methods

MEDLINE, Embase, The Cochrane library, PubMed, Scopus, PsycInfo, and grey literature databases were searched from inception to 26 April 2023. Records were eligible if they described sex differences in the treatment of adults with FH.

Results

Of 4432 publication

SUBMITTER: Iatan I 

PROVIDER: S-EPMC11400737 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature