Predictive biomarkers of mortality in patients with severe COVID-19 hospitalized in intensive care unit.

ABSTRACT:

Objectives

This study was performed to identify predictive markers of worse outcomes in patients with severe COVID-19 in an intensive care unit.

Methods

Sixty patients with severe COVID-19, hospitalized in the Intensive Care Unit (ICU) between March and July 2021, were stratified into two groups according to the outcome survivors and non-survivors. After admission to the ICU, blood samples were collected directly for biomarker analysis. Routine hematological and biochemical biomarkers, as well as serum levels of cytokines, chemokines, and immunoglobulins, were investigated.

Results

Lymphopenia, neutrophilia, and thrombocytopenia were more pronounced in non-surviving patients, while the levels of CRP, AST, creatinine, ferritin, AST, troponin I, urea, magnesium, and pot

SUBMITTER: Dos Santos Medeiros SMFR 

PROVIDER: S-EPMC11401048 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature