Development and validation of a prognostic nomogram for esophageal cancer patients based on SEER Asian population.

ABSTRACT: This study aims to develop and validate a nomogram for predicting overall survival (OS) in Asian patients with Esophageal Cancer (EC). Data from Asian EC patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database. The patients were randomly divided into training and validation cohorts in a 7:3 ratio. The Least Absolute Shrinkage and Selection Operator (LASSO) regression was used for initial variable selection, followed by multivariate Cox regression analysis to identify independent prognostic factors. A nomogram was subsequently constructed based on these factors. The predictive performance of the nomogram was evaluated using receiver operating characteristic (ROC) curves and calibration curves, while the clinical utility of the nomogram was assessed throu

SUBMITTER: Guo X 

PROVIDER: S-EPMC11401934 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature