Retinal Vascular Caliber Association with Nonperfusion and Diabetic Retinopathy Severity Depends on Vascular Caliber Measurement Location.

ABSTRACT:

Purpose

To evaluate the association of retinal nonperfusion and diabetic retinopathy (DR) severity with location of vascular caliber measurement using ultrawide field (UWF) imaging.

Design

Retrospective image review.

Participants

Adults with diabetes mellitus.

Methods

All images from subjects with same-day UWF fluorescein angiography (FA) and color imaging were evaluated. Predominantly peripheral lesions (PPL) and DR severity were graded from UWF color images. Nonperfusion was quantified using UWF-FA in defined retinal regions [posterior pole (PP), mid-periphery (MP), far-periphery (FP)]. Retinal vessel calibers were measured at an optic disc centered inner and outer zone.

Main outcome measures

Nonperfusion index (NPI) in the PP, MP and FP. Mean arteriol

SUBMITTER: Ashraf M 

PROVIDER: S-EPMC11401977 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature