Coronary Artery Calcium for Risk Stratification Among Persons With Very High HDL Cholesterol.

ABSTRACT:

Background

Compared to normal high-density lipoprotein (HDL) cholesterol values, very high HDL cholesterol is associated with a higher incidence of mortality and atherosclerotic cardiovascular disease (ASCVD). As such, clinical risk stratification among persons with very high HDL cholesterol is challenging.

Objectives

Among persons with very high HDL cholesterol, the purpose was to determine the prevalence of coronary artery calcium (CAC) and compare the association between traditional risk factors vs CAC for all-cause mortality and ASCVD.

Methods

The primary analysis was completed among 446 participants from the Cedars-Sinai Medical Center of the CAC Consortium with very high HDL cholesterol (≥77 mg/dL in men, ≥97 mg/dL in women). Cox proportional hazards regression

SUBMITTER: Razavi AC 

PROVIDER: S-EPMC11402127 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature