Is the ICP pulse waveform P2/P1 ratio during -6° head-down tilt associated with relative VO₂ peak? A non-invasive intracranial compliance monitoring approach.

ABSTRACT:

Background

Spaceflights influence intracranial compliance (ICC). P2/P1 ratio, from the intracranial pressure (ICP) waveform, provides information about ICC. Additionally, non-invasive methods for ICC monitoring are needed for spaceflights. Furthermore, astronauts try to maintain good levels of cardiorespiratory fitness before and during spaceflights, not only to sustain exploratory missions, but also to prevent diseases in extreme environments.

Objective

to correlate cardiorespiratory fitness levels with the P2/P1 ratio during a microgravity analog [-6° head-down tilt (HDT)].

Method

34 individuals (11 women), mean age of 31.7 (±6.3) years and BMI 24.2 (±3.2) performed a cardiopulmonary exercise testing (CPET) with an incremental protocol on a cycle ergometer to determ

SUBMITTER: Mendes Zambetta R 

PROVIDER: S-EPMC11402318 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature