Maternal autoimmune disease and offspring risk of haematological malignancies: a case-control study.

ABSTRACT:

Background

Autoimmune diseases are known to be associated with an increased risk of cancer. Whether maternal immune dysregulation can have an impact on the development of haematological malignancies in offspring remains uncertain. Therefore, we explored the association between offspring risk of haematological malignancies and maternal autoimmune disease using a real-world nationwide population-based study.

Methods

In this case-control study, we identified 2172 children with haematological malignancies between 2004 and 2019 from Taiwan's National Health Insurance program and compared them with population-based controls without haematologic malignancies, who were matched with each individual at a ratio of 1:4. The medical information of the autoimmune mothers were obtained fro

SUBMITTER: Liu SN 

PROVIDER: S-EPMC11402410 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature