Herpesviruses and human papillomaviruses in saliva and biopsies of patients with orofacial tumors.

ABSTRACT:

Objectives

To determine the prevalence and association of HPV and Herpesviruses in saliva and tissue samples of patients with orofacial tumors.

Methods

Biopsies of tumors were done, and saliva samples were collected from patients with orofacial tumors for the determination of viruses using nested multiplex PCR. Independent variables were sex, age, comorbidities, tumor stage, and length of stay. Outcome variables were the presence or absence of herpesviruses and HPV. Descriptive summaries and inferential statistics were done.

Results

A hundred patients were included in the study. Prevalence of herpesviruses and HPV were 17.6 % and 57.0 % in tumors, and 48.3 % and 60.0 % in the saliva of patients respectively. Herpesviruses detected included EBV (21.3 %), HHV-7 (11.2 %)

SUBMITTER: Blankson PK 

PROVIDER: S-EPMC11402418 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature