Regulatory T-cell phenotypes in prenatal psychological distress.

ABSTRACT:

Background

Experiencing symptoms of psychological distress during pregnancy is common and has been linked to dysregulated immune functioning. In this context, immunoregulatory function is especially relevant because of its crucial role in establishment and maintenance of healthy pregnancy. However, little research has examined associations between women's prenatal psychological distress and immunoregulatory biomarkers. We investigated how symptoms of depression, anxiety, and stress relate to circulating levels of regulatory T-cells (Tregs).

Materials and methods

Pregnant Latina women were assessed at around 12 weeks of pregnancy (N = 82). These assessments included blood draws and self-report questionnaires assessing symptoms of depression, state anxiety, pregnancy-related a

SUBMITTER: Wiley KS 

PROVIDER: S-EPMC11402516 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature