Development and validation of a nomogram for predicting advanced liver fibrosis in patients with chronic hepatitis B.

ABSTRACT:

Background

The progression of chronic hepatitis B (CHB) to liver fibrosis and even cirrhosis is often unknown to patients, but noninvasive markers capable of effectively identifying advanced liver fibrosis remains absent.

Objective

Based on the results of liver biopsy, we aimed to construct a new nomogram to validate the stage of liver fibrosis in CHB patients by the basic information of CHB patients and routine laboratory tests.

Methods

Patients with CHB diagnosed for the first time in the First Affiliated Hospital of Anhui Medical University from 2010 to 2018 were selected, and their basic information, laboratory tests and liver biopsy information were collected. Eventually, 974 patients were enrolled in the study, while all patients were randomized into a training

SUBMITTER: Han K 

PROVIDER: S-EPMC11403247 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature