Characteristics and long-term mortality of individuals with MASLD, MetALD, and ALD, and the utility of SAFE score.

ABSTRACT:

Background & aims

The new nomenclature of steatotic liver disease (SLD) was recently launched with sub-classifications of metabolic dysfunction-associated SLD (MASLD), MASLD with increased alcohol intake (MetALD), and alcohol-related liver disease (ALD). Herein, we aimed to evaluate the characteristics and long-term outcomes associated with these subgroups and the utility of non-invasive biomarkers.

Methods

Using NHANES III (the third National Health and Nutrition Examination Survey) and linked mortality data, all adult participants with available ultrasonographic liver steatosis status were included. Those with viral hepatitis, incomplete data on alcohol consumption, cardiometabolic risk, and missing data that hindered Steatosis-associated Fibrosis Estimator (SAFE) score ca

SUBMITTER: Sripongpun P 

PROVIDER: S-EPMC11403267 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature