Oxylipins in Breast Implant-Associated Systemic Symptoms.

ABSTRACT:

Background

A subset of females with breast implants have reported a myriad of nonspecific systemic symptoms collectively termed systemic symptoms associated with breast implants (SSBI). SSBI symptoms are similar to manifestations associated with autoimmune and connective tissue disorders. Breast tissue is rich in adipose cells, comprised of lipids. Insertion of an implant creates an oxidative environment leading to lipid oxidation. Oxylipins can influence immune responses and inflammatory processes.

Objectives

In this study we explored the abundance of a spectrum of oxylipins in the periprosthetic tissue surrounding the breast implant. Because oxylipins are immunogenic, we sought to determine if they were associated with the SSBI patients. We have also attempted to determine

SUBMITTER: Khan I 

PROVIDER: S-EPMC11403815 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature