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ABSTRACT: Background
To detect preload responsiveness in patients ventilated with a tidal volume (Vt) at 6 mL/kg of predicted body weight (PBW), the Vt-challenge consists in increasing Vt from 6 to 8 mL/kg PBW and measuring the increase in pulse pressure variation (PPV). However, this requires an arterial catheter. The perfusion index (PI), which reflects the amplitude of the photoplethysmographic signal, may reflect stroke volume and its respiratory variation (pleth variability index, PVI) may estimate PPV. We assessed whether Vt-challenge-induced changes in PI or PVI could be as reliable as changes in PPV for detecting preload responsiveness defined by a PLR-induced increase in cardiac index (CI) ≥ 10%.Methods
In critically ill patients ventilated with Vt = 6 mL/kg PBW and no spont
SUBMITTER: Bruscagnin C
PROVIDER: S-EPMC11404033 | biostudies-literature | 2024 Sep
REPOSITORIES: biostudies-literature