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ABSTRACT: Introduction
This study evaluated constipation, including reduced bowel movement frequency and difficult defecation, in patients with isolated rapid eye movement sleep behavior disorder (IRBD), which is prodromal Parkinson's disease (PD) or dementia with Lewy bodies (DLB) in middle-aged and older adults.Methods
We used a validated Japanese version of the Constipation Assessment Scale (CAS-J) to evaluate bowel habits over 1 month in 117 men aged 50-86 years and 34 women aged 56-86 years with video-polysomnography-confirmed IRBD and 22 controls. Furthermore, we performed a longitudinal assessment of outcomes at follow-up visits.Results
The CAS-J score was higher in the 22 IRBD patients than in 22 age- and gender-matched paired controls. In 151 IRBD patients, the CAS-J
SUBMITTER: Miyamoto T
PROVIDER: S-EPMC11404085 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature