Prescription and switching patterns of direct oral anticoagulants in patients with atrial fibrillation.

ABSTRACT:

Background

The patterns of direct oral anticoagulant (DOAC) selection and switching to a different oral anticoagulant (OAC) in patients with atrial fibrillation (AF) are unknown.

Objectives

To describe temporal patterns in first DOAC prescriptions, estimate the incidence, and identify predictors of switching to a different OAC within 1 year in OAC-naive AF patients.

Methods

In this retrospective cohort study, using a near-nationwide prescription registry (IQVIA, the Netherlands), we determined the number of patients per month initiated on each DOAC and identified predictors of switching within 1 year with robust Poisson regression.

Results

We included 94,874 patients. From November 2015 to November 2019, the monthly use of apixaban (n = 366 to n =

SUBMITTER: de Vries TAC 

PROVIDER: S-EPMC11404132 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature