Investigation of end-stage kidney disease risk prediction in an ethnically diverse cohort of people with type 2 diabetes: use of kidney failure risk equation.

ABSTRACT:

Introduction

The four variable kidney failure (KF) risk equation (KFRE) is recommended to estimate KF risk (ie, need for dialysis or kidney transplantation). Earlier referral to clinical kidney services for people with high-risk of kidney failure can ensure appropriate care, education and support are in place pre-emptively. There are limited data on investigating the performance of KFRE in estimating risk of end-stage kidney disease (ESKD) in people with type 2 diabetes mellitus (T2DM) and chronic kidney disease (CKD). The primary ESKD endpoint event was defined as estimated glomerular filtration rate (eGFR) <10 mL/min/1.73 m² and secondary endpoint eGFR <15 mL/min/1.73 m².

Research design and methods

We studied 7296 people (30% women, 41% African-Carib

SUBMITTER: Goubar A 

PROVIDER: S-EPMC11404155 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature