Longitudinal change in cardiorespiratory fitness and the association with cardiovascular disease and all-cause mortality in young Asian men: a cohort study.

ABSTRACT:

Introduction

Cardiorespiratory fitness (CRF) in young adulthood is a determinant of chronic disease risk. To better understand whether CRF might also behave as a modifiable risk factor, we examined the associations between longitudinal changes in 2.4 km run times and health outcomes in a cohort of healthy young men.

Methods

Our dataset comprised individual run times and health outcomes captured in four national registries. Cox proportional hazards models were used to examine the association between baseline run times and relative hazards of first major adverse cardiovascular events (MACE) and all-cause mortality (ACM). Relative hazards associated with longitudinal change in run times were estimated using models that were adjusted for run-time at baseline.

Results

The

SUBMITTER: Gorny AW 

PROVIDER: S-EPMC11404237 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature