Quantitative analysis of nortriptyline's analgesic properties: a comparative systematic review and meta-analysis.

ABSTRACT:

Objectives

This study aims to quantitatively analyse nortriptyline's analgesic potency, safety and tolerability.

Design

Systematic review and meta-analysis.

Data sources

The systematic search was conducted in Scopus, Web of Science and PubMed in February 2023.

Eligibility criteria for selecting studies

Clinical trials evaluating the efficacy of nortriptyline in reducing pain scores (open-label studies and comparisons of nortriptyline with placebo or other analgesics) in different pain types were included.

Data extraction and synthesis

The data extraction procedure and the screening phases were carried out based on predetermined eligibility criteria. To pool the data, the standardised mean difference (SMD) and standardised mean change (SMC) methods, along

SUBMITTER: Hashemzadeh S 

PROVIDER: S-EPMC11404244 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature