Associations between epicardial, visceral, and subcutaneous adipose tissue with diastolic function in men with and without HIV.

ABSTRACT:

Background

People with HIV (PWH) are at greater risk for diastolic dysfunction compared with persons without HIV (PWOH). An increase in visceral adipose tissue is common among PWH and greater visceral adipose tissue is associated with diastolic dysfunction among PWOH. We investigated associations of visceral adipose tissue, subcutaneous adipose tissue, and other fat depots with subclinical diastolic dysfunction among men with and without HIV (MWH and MWOH).

Design

Cross-sectional analysis of MWH and MWOH in the Multicenter AIDS Cohort Study (MACS).

Methods

Participants underwent echocardiography for diastolic dysfunction assessment and CT scanning including subcutaneous, visceral, epicardial, and liver adiposity measurements. Diastolic dysfunction was defined by chara

SUBMITTER: Goldberg RL 

PROVIDER: S-EPMC11404677 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature