Identification of the shared gene MXD3 signatures and biological mechanism in patients with hip pain and prostate cancer.

ABSTRACT: Prostate cancer (PRAD) is recognized as having a significant effect on systemic illnesses. This study examined possible immune cells, metabolic pathways, and genes that may explain the interaction between PRAD and hip pain. We used information retrieved from the Cancer Genome Atlas and the Gene Expression Omnibus databases. To find common genes, we utilized differential expression analysis and weighted gene co-expression network analysis. The genes that were shared were subjected to pathway enrichment studies using Gene Ontology and the Kyoto Encyclopedia of Genes and Genomes. Additionally, hub genes were analyzed using LASSO regression, and a receiver operating characteristic curve was generated based on the screening outcomes. The genes for the nodes were chosen in a protein-protein inte

SUBMITTER: Huang L 

PROVIDER: S-EPMC11404923 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature