Childhood-onset systemic lupus erythematosus: A descriptive and comparative study of clinical, laboratory, and treatment characteristics in two populations.

ABSTRACT:

Objective

The aim of this study was to characterize childhood-onset systemic lupus erythematosus (SLE) in two large cohorts from Turkey and the United States.

Methods

Patients diagnosed with childhood-onset SLE who fulfilled the 1997 American College of Rheumatology classification criteria for SLE from four reference centers in Turkey and the University of Pittsburgh School of Medicine in the United States were included in this study. A comparative analysis was conducted to evaluate the similarities and differences in clinical and laboratory features, damage accrual, and treatment experiences between the two populations.

Results

A total of 174 patients with childhood-onset SLE were included in this study (108 patients from Turkey and 66 patients from the United States

SUBMITTER: Kavrul Kayaalp G 

PROVIDER: S-EPMC11405132 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature