Central venous access device adverse events in pediatric patients with cancer: a systematic review and meta-analysis.

ABSTRACT:

Purpose

To systematically review the proportion and incidence of CVAD-associated complications in pediatric patients with cancer.

Methods

PubMed, Embase, and the Cumulative Index of Nursing and Allied Health Literature were searched from 2012 to 2022. Cohort studies and the control arm of randomized controlled trials, which reported CVAD-associated complications in pediatric patients aged 0-18 years, were included. CVAD complications were defined as CVAD failure, central line-associated bloodstream infection (CLABSI), local infection, occlusion, CVAD-associated venous thromboembolism, dislodgement/migration, breakage/rupture, and dehiscence. The pooled proportion and incidence rate (IR) for each CVAD-associated complication were reported.

Results

Of 40 included studie

SUBMITTER: Nunn JL 

PROVIDER: S-EPMC11405478 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature