Trophectoderm grade as a predictor of beta human-chorionic gonadotropin rise in early pregnancy.

ABSTRACT:

Purpose

To evaluate the association, if any, between the grade of the trophectoderm (TE) and the rate at which β-human-chorionic gonadotropin (β-HCG) rises in early pregnancy.

Methods

This is a retrospective cohort study including 1116 singleton clinical pregnancies resulting from in vitro fertilization with single day 5 blastocyst transfer at an academic fertility center. TE quality was assessed by trained embryologists employing standard criteria. Three groups were formed based on the TE grade: grade A (n = 358), grade B (n = 628), and grade C (n = 130). Main outcome measure was the rise (%) in serum levels of β-HCG (days 12 to 14 post embryo transfer), using the following formula [(β-HCG D14 - β-HCG D12) * 100/β-HCG D12].

Results

Fresh embryo transfers accounted fo

SUBMITTER: Vagios S 

PROVIDER: S-EPMC11405584 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature