Repolarization Injury and Occurrence of Torsades de Pointes During Acute Takotsubo Syndrome.

ABSTRACT:

Background

During takotsubo syndrome (TS), QTc prolongation is common, reflecting repolarization injury and providing the substrate for torsades de pointes (TdP). TdP has been reported sporadically in TS, yet QTc prolongation and TdP risk are often overlooked during management.

Objectives

In TS patients, we sought to document TdP incidence, characteristics of patients with TdP, and association of QTc with postdischarge survival.

Methods

Among consecutive TS patients at a single institution, we documented admission and discharge QTc, TdP incidence, and postdischarge 1-year mortality from 2006 to 2019. For perspective regarding TdP-TS risk, we characterized all published TdP cases from 2003 to 2022.

Results

Of 259 patients, median age was 68 (range: 59-77) years;

SUBMITTER: Vemmou E 

PROVIDER: S-EPMC11406033 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature