A Novel Echocardiographic Parameter to Confirm Low-Gradient Aortic Stenosis Severity.

ABSTRACT:

Background

In patients with low-gradient (LG) aortic stenosis (AS), confirming disease severity and indication of intervention often requires dobutamine stress echocardiography (DSE) or aortic valve calcium scoring by computed tomography. We hypothesized that the mean transvalvular pressure gradient to effective orifice area ratio (MG/EOA, in mm Hg/cm²) measured during rest echocardiography identifies true-severe AS (TSAS) and is associated with clinical outcomes in patients with low-flow, LG-AS.

Objectives

The purpose of this study was to evaluate the diagnostic and prognostic value of MG/EOA ratio.

Methods

The diagnostic accuracy of MG/EOA ratio to identify TSAS was retrospectively assessed in: 1) an in vitro data set obtained in a circulatory model inclu

SUBMITTER: Hecht S 

PROVIDER: S-EPMC11406036 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature