Air Pollution and Parkinson Disease in a Population-Based Study.

ABSTRACT:

Importance

The role of air pollution in risk and progression of Parkinson disease (PD) is unclear.

Objective

To assess whether air pollution is associated with increased risk of PD and clinical characteristics of PD.

Design, setting, and participants

This population-based case-control study included patients with PD and matched controls from the Rochester Epidemiology Project from 1998 to 2015. Data were analyzed from January to June 2024.

Exposures

Mean annual exposure to particulate matter with a diameter of 2.5 µm or less (PM2.5) from 1998 to 2015 and mean annual exposure to nitrogen dioxide (NO2) from 2000 to 2014.

Main outcomes and measures

Outcomes of interest were PD risk, all-cause mortality, presence of tremor-predominant vs akinetic rigid PD, a

SUBMITTER: Krzyzanowski B 

PROVIDER: S-EPMC11406396 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature