The butyrate-producing and spore-forming bacterial genus Coprococcus as a potential biomarker for neurological disorders.

ABSTRACT: The host-intestinal microbiome interaction has gained much scientific attention in the past two decades, boosted by advances in DNA sequencing and cultivation techniques. An accumulating amount of evidence shows that gut microbes play crucial roles in gut homeostasis, immune system education, and are associated with quality-of-life indicators. Beneficial health factors are associated with the digestion of dietary fibres in the colon and the subsequent production of short-chain fatty acids, including acetate, propionate, and butyrate. Coprococcus is a butyrate-producing genus in the phylum Firmicutes, and its abundance is inversely correlated with several neuropsychological and neurodegenerative disorders. Case-control studies provide strong evidence of decreased abundance of Copr

SUBMITTER: Notting F 

PROVIDER: S-EPMC11406416 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature