New phenotyping questionnaire for diagnosing sarcoidosis-associated small fiber neuropathy.

ABSTRACT: Small fiber neuropathy is a common complication in patients with sarcoidosis and its prevalence is estimated at 40-86%. The underlying mechanism influences the presentation of small fiber neuropathy. For example, patients with metabolic diseases are often associated with a classic length-dependent small fiber neuropathy pattern, while patients with inflammatory diseases are more often present with a non-length-dependent small fiber neuropathy. Detailed phenotyping may be useful to improve diagnostic efficiency, as a clue to underlying mechanisms and as a precondition for personalized medicine. This study examined four phenotypes distinguishing between length-dependent and non-length-dependent presentation with a new subdivision for continuous and intermittent presentation. Forty-eight sarc

SUBMITTER: Raasing LRM 

PROVIDER: S-EPMC11406462 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature