Clinical and diagnostic features of central nervous system tuberculosis in Indian children - a descriptive study.

ABSTRACT:

Background

Children with tuberculous meningitis (TBM) present with diagnostic challenges as they often have atypical clinical features.

Objective

To describe the baseline characteristic features of children diagnosed with central nervous system (CNS) TB (TBM and tuberculoma).

Design

Retrospective descriptive study.

Methods

Children less than 12 years presenting with neurological signs and symptoms were assessed for a therapeutic TBM trial eligibility. The results of their clinical, laboratory, neuroimaging, cerebrospinal fluid evaluations were analysed for TBM diagnosis.

Results

Of 600 children evaluated, 61(10%) had CNS tuberculosis; TBM 47, tuberculoma 14. 20(33%) had definite TBM. Mean age of children with TBM was 5 ± 3.4 years. Of 47, 13(28%), 21(45%

SUBMITTER: Daniel BD 

PROVIDER: S-EPMC11406600 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature