Atlas of telomeric repeat diversity in Arabidopsis thaliana.

ABSTRACT:

Background

Telomeric repeat arrays at the ends of chromosomes are highly dynamic in composition, but their repetitive nature and technological limitations have made it difficult to assess their true variation in genome diversity surveys.

Results

We have comprehensively characterized the sequence variation immediately adjacent to the canonical telomeric repeat arrays at the very ends of chromosomes in 74 genetically diverse Arabidopsis thaliana accessions. We first describe several types of distinct telomeric repeat units and then identify evolutionary processes such as local homogenization and higher-order repeat formation that shape diversity of chromosome ends. By comparing largely isogenic samples, we also determine repeat number variation of the degenerate and variant te

SUBMITTER: Tao Y 

PROVIDER: S-EPMC11406999 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature