Reference values for exhaled nitric oxide in healthy children aged 6-18 years in China: a cross-sectional, multicenter clinical study.

ABSTRACT:

Background

The reference values of eNO have certain differences among people of different countries and races. We aimed to obtain the reference value of eNO in healthy children and adolescents (6-18 years old) in China and to explore the associations between the reference values with ages, gender, heights, BMI, and regions.

Methods

We measured FeNO₅₀ levels in 5949 healthy Chinese children and adolescents, FeNO₂₀₀ and CaNO levels in 658 participants from 16 provinces of 7 administrative areas in China aged 6-18. All persons were studied after obtaining informed consent from children and their parents.

Results

The mean FeNO₅₀ of 5949 Chinese children and adolescents aged 6-18 years was 14.1 ppb, with a 95% confidence interval of 1-38.1

SUBMITTER: Liu Y 

PROVIDER: S-EPMC11407013 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature