Quantitative sensory testing and chronic pain syndromes: a cross-sectional study from TwinsUK.

ABSTRACT:

Objective

The chronic pain syndromes (CPS) include syndromes such as chronic widespread pain (CWP), dry eye disease (DED) and irritable bowel syndrome (IBS). Highly prevalent and lacking pathognomonic biomarkers, the CPS are known to cluster in individuals in part due to their genetic overlap, but patient diagnosis can be difficult. The success of quantitative sensory testing (QST) and inflammatory biomarkers as phenotyping tools in conditions such as painful neuropathies warrant their investigation in CPS. We aimed to examine whether individual QST modalities and candidate inflammatory markers were associated with CWP, DED or IBS in a large, highly phenotyped population sample.

Design

Cross-sectional study.

Setting

Community-dwelling cohort.

Participants

Twins

SUBMITTER: Rhee A 

PROVIDER: S-EPMC11407192 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature