Neural processing of audiovisual and painful analogue trauma and its relationship with subsequent audiovisual and pain intrusions.

ABSTRACT: Background: Posttraumatic stress disorder and medically unexplained pain frequently co-occur. While pain is common during traumatic events, the processing of pain during trauma and its relation to audiovisual and pain intrusions is poorly understood.Objective: Here we investigate neural activations during painful analogue trauma, focusing on areas that have been related to threat and pain processing, and how they predict intrusion formation. We also examine the moderating role of cumulative lifetime adversity.Methods: Sixty-five healthy women were assessed using functional magnetic resonance imaging. An analogue trauma was induced by an adaptation of the trauma-film paradigm extended by painful electrical stimulation in a 2 (film: aversive, neutral) x 2 (pain: pain, no

SUBMITTER: Miedl SF 

PROVIDER: S-EPMC11407396 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature