Diagnosis of brucellosis: Combining tests to improve performance.

ABSTRACT:

Introduction

Brucellosis, a zoonotic infectious disease caused by bacteria of the genus Brucella, remains a significant global health concern in many parts of the world. Traditional diagnostic methods, including serological tests, suffer from limitations, including low sensibility and high false-positive rates, emphasizing the need for improved diagnostic strategies. In this study, we aimed to optimize diagnostic accuracy by reevaluating serological tests and exploring novel diagnostic algorithms.

Methods

A retrospective observational study was conducted using sera collected between June 2012 and June 2023 at the French National Reference Center for Brucella. Various serological tests, including Rose Bengal plate test (RBT), standard agglutination test (SAT), Brucellacapt, a

SUBMITTER: Loubet P 

PROVIDER: S-EPMC11407618 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature