Different strategies in left ventricle unloading during venoarterial extracorporeal membrane oxygenation: A network meta-analysis.

ABSTRACT:

Background

Left ventricular (LV) overload is a frequent complication during VA-ECMO associated with poor outcomes. Many strategies of LV unloading have been documented but lack of evidence shows which is better. We conducted a network meta-analysis to compare different LV unloading strategies.

Methods

We searched databases for all published studies on LV unloading strategies during VA-ECMO. The pre-defined primary outcome was all-cause mortality.

Results

45 observational studies (34235 patients) were included. The Surface Under the Cumulative Ranking values (SUCRA) demonstrated that compared to no unloading strategy (15.4 %), IABP (73.8 %), pLVAD (60.8 %), atrial septostomy (51.2 %), catheter venting (48.8 %) were all associated with decreased all-cause mortality, in

SUBMITTER: Zhang H 

PROVIDER: S-EPMC11408045 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature