Tetrakis(trimethylsilyl)silane as a standard compound for fast spinning Solid-State NMR experiments.

ABSTRACT: The development of magic angle spinning (MAS) at rates ranging from 30 kHz to greater than 100 kHz has substantially advanced solid-state nuclear magnetic resonance (SSNMR) spectroscopy ¹H-detection methods. The small rotors required for such MAS rates have a limited sample volume and low ¹³C-detection sensitivity, rendering the traditional set of standard compounds for SSNMR insufficient or highly inconvenient for shimming and magic-angle calibration. Additionally, the reproducibility of magic angle setting, chemical shift referencing, and probe position can be especially critical for SSNMR experiments at high fields. These conditions suggest the need for a high signal-to-noise ratio (SNR) ¹H-detection standard compound, which is preferably multi-purpose,

SUBMITTER: Han R 

PROVIDER: S-EPMC11408081 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature