The first review on prenatal drug exposure and ocular malformation occurrence.

ABSTRACT: Even though a non-negligible portion of congenital eye anomalies has a clear genetic origin, an etiology is not found for most patients. Prenatal medication exposure is recognized to be involved in fetal malformations and several medications are specifically known to alter eye morphogenesis during embryonic development leading to congenital eye defects. We explored and reviewed the role of medications described in the genesis of ocular malformations, a role that has been little evaluated and probably still underestimated especially since several studies have shown the wide exposure of pregnant women to medication. We present our results in two sections; the first describes medications reported to be associated with ocular malformations in humans; the second details medications responsible

SUBMITTER: Dubucs C 

PROVIDER: S-EPMC11408236 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature