Brain topology underlying executive functions across the lifespan: focus on the default mode network.

ABSTRACT:

Introduction

While traditional neuroimaging approaches to the study of executive functions (EFs) have typically employed task-evoked paradigms, resting state studies are gaining popularity as a tool for investigating inter-individual variability in the functional connectome and its relationship to cognitive performance outside of the scanner.

Method

Using resting state functional magnetic resonance imaging data from the Human Connectome Project Lifespan database, the present study capitalized on graph theory to chart cross-sectional variations in the intrinsic functional organization of the frontoparietal (FPN) and the default mode (DMN) networks in 500 healthy individuals (from 10 to 100 years of age), to investigate the neural underpinnings of EFs across the lifespan.

R

SUBMITTER: Menardi A 

PROVIDER: S-EPMC11408365 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature