The value of SDC2 and Septin9 combined with serum tumor markers in early diagnosis of colorectal cancer.

ABSTRACT:

Objective

The aim of this study is to evaluate the significance of combined detection of Septin9 and syndecan-2 (SDC2) methylation markers and serum tumor markers for the early diagnosis of colorectal cancer.

Methods

A total of 116 patients diagnosed with colorectal cancer between December 2022 and February 2024 were designated as the colorectal cancer group. Additionally, 31 patients with colorectal adenoma were assigned to the adenoma group, while 44 individuals undergoing routine physical examinations were included in the control group. Concentrations of Septin9, SDC2, fecal occult blood (FOB), and four tumor markers-carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199), carbohydrate antigen 125 (CA125), and carbohydrate antigen 724 (CA724)-were measured. Diagn

SUBMITTER: Zou CS 

PROVIDER: S-EPMC11408399 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature