Overview of 37 Tear Substitutes in Europe Based on Various Physicochemical Parameters.

ABSTRACT:

Introduction

Dry eye disease (DED) is one of the most prevalent eye conditions worldwide, with artificial tears serving as a primary treatment option. Despite their wide availability on the European market, there is a lack of established classifications based on their physicochemical properties. The aim of our study was therefore (i) to develop an analytical method that measures the concentration and the molecular weight (MW) of the hyaluronic acid (HA) in commercialized products, and (ii) to propose an overview based on their various physicochemical parameters.

Methods

The intrinsic viscosity and MW of the HA, as well as osmolarity, pH, rheological profile, and viscosity, were measured or determined. A specific method was developed to measure the average intrinsic viscosity

SUBMITTER: Paschier A 

PROVIDER: S-EPMC11408415 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature