Correlation between circulating lipoprotein(a) levels and cardiovascular events risk in patients with type 2 diabetes.

ABSTRACT:

Background

High circulatory lipoprotein(a) [Lp(a)] concentration promotes atherosclerosis; however, its efficacy in predicting the extent of atherosclerotic coronary heart disease (CHD) with coronary artery obstruction and major adverse cardiovascular events (MACEs) in diabetic patients remains questionable. This study aimed to examine whether elevated circulating Lp(a) levels exacerbate CHD and to assess their utility in predicting MACEs in individuals diagnosed with type 2 diabetes mellitus (T2DM).

Methods

In total, 4332 patients diagnosed with T2DM who underwent coronary angiography (CAG) were included and categorized into two groups (CHD and non-CHD) based on the CAG results. We used a correlation analysis to explore the potential links between the levels of circulating

SUBMITTER: Gu JX 

PROVIDER: S-EPMC11408807 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature